上海浩洋生物科技有限公司

 PD0325901
  • PD0325901
  • PD0325901

    参考价格: ¥1806.00
    品  牌:invivogen
    产品型号:inh-pd32 (2 mg)
    所在地区:上海
    上架时间:2013年03月18日
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    PD0325901
    产品名称:PD0325901
    规格:2 mg
    货号:inh-pd32
    厂商:invivogen
    产品介绍:
    Working concentration: 0.5 µM
    CAS number: 391210-10-9
    Purity: >98% (HPLC)
    Molecular weight: 482.19
    Solubility: DMSO, ethanol, DMF (20 mg/ml)
    PD0325901 is a synthetic organic molecule that selectively binds to and inhibits mitogen-activated protein kinase kinase (MEK). The MEK/ERK signaling pathway plays an important role in the self-renewing state of ES cells [1]. Inhibition of this pathway combined with the inhibition of other signaling pathways has been shown to improve the efficiency of iPS cell generation. Combination of PD0325901 with a TGF-β receptor inhibitor was found to improve the reprogramming of OSKM-infected human fibroblasts [2].