上海浩洋生物科技有限公司

 PD98059
  • PD98059
  • PD98059

    参考价格: ¥1302.00
    品  牌:invivogen
    产品型号:tlrl-pd98 (10 mg)
    所在地区:上海
    上架时间:2013年03月18日
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    PD98059
    产品名称:PD98059
    规格:10 mg
    货号:tlrl-pd98
    厂商:invivogen
    产品介绍:
    Working concentration: 50-100 μM
    CAS number: 167869-21-8
    Synonym: 2’-Amino-3’-methoxyflavone
    Formula: C16H13NO3
    Molecular weight: 267.28
    Solubility: DMSO (6.5 mg/ml), ethanol (0.6 mg/ml)
    Purity: >99% (HPLC, TLC)
    PD98059 is a potent and selective inhibitor of MAP kinase kinase (also known as MAPK/ERK kinase or MEK kinase) [1]. It mediates its inhibitory properties by binding to the ERK-specific MAP kinase MEK, therefore preventing phosphorylation of ERK1/2 (p44/p42 MAPK) by MEK1/2. MAPK ERK1/2 is involved in TLR-induced production of cytokines[2, 3].