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  • pUNO-hMBL2

    参考价格: ¥5334.00
    品  牌:invivogen
    产品型号:puno-hmbl2 (1 disk)
    所在地区:上海
    上架时间:2013年03月26日
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    pUNO-hMBL2
    产品名称:pUNO-hMBL2
    规格:1 disk
    货号:puno-hmbl2
    厂商:invivogen
    产品介绍:
    pUNO bearing human MBL2 ORF
    Gene: MBL2
    Alias: MBP1
    Species: Human
    Backbone: pUNO
    Selection: Blasticidin
    pUNO bearing mouse MBL2 ORF
    Gene: MBL2
    Alias: MBP1
    Species: Mouse
    Backbone: pUNO
    Selection: Blasticidin
    Mannose-binding lectin (MBL), also called mannose-binding protein (MBP) is a member of the collectin family of proteins in which collagen structures are associated with carbohydrate-recognizing lectin domains [1]. MBL is a serum protein that binds a large variety of sugar moieties expressed by bacteria, viruses, protozoa and helminths through a pattern-recognition mode of detection [2]. MBL can mediate phagocytosis of microorganisms and induce inflammatory responses. MBL can also activate the complement system via MBL-associated serine proteases (MASPs). MBL is encoded by a single human gene, mbl2 (mbl1 is a pseudogene) and by two mouse genes, mbl1 and mbl2 [3].