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 Anti-Human CD40 (clone 5C3) eFluor 450
  • Anti-Human CD40 (clone 5C3) eFluor 450
  • Anti-Human CD40 (clone 5C3) eFluor 450

    参考价格: ¥3348.00
    品  牌:eBioscience
    产品型号:48-0409-42 (100 tests)
    所在地区:上海
    上架时间:2012年12月20日
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    Anti-Human CD40 (clone 5C3) eFluor 450
    产品名称:Anti-Human CD40 (clone 5C3) eFluor 450
    规格:100 tests
    货号:48-0409-42
    厂商:eBioscience
    产品介绍:
    Also known as: TNFRSF5
    Clone: 5C3
    Host Mouse
    Isotype IgG1, kappa
    Reactivity Human
    Conjugate eFluor 450
    Laser Violet Laser
    Excite 405 nm
    Reported Applications Flow Cytometric Analysis
    Description: The 5C3 monoclonal antibody reacts with human CD40, a 45-50 kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development and maturation by inducing Ig isotype-switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. 5C3 is reported to be used for activation of B cells in in vitro functional assays.
    eBioscience 48-0409-42 Anti-Human CD40 (clone 5C3) eFluor® 450, 100 tests 3348
    eBioscience 48-0409-41 Anti-Human CD40 (clone 5C3) eFluor® 450, 25 tests 1308