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重组人干扰素-α1A Recombinant Human IFN-α1a

重组人干扰素-α1A Recombinant Human IFN-α1a

参考价格:¥11600.00
产品型号:C22-106-01-1mg
所在地区:华东 上海
上架时间:2017-11-22
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    IFN a 1a Human
    Interferon-Alpha 1a Human Recombinant
    Catalog No. CYT-520
    Synonyms:
    Interferon-alpha 1a, IFN-a 1a, IFN alpha 1a.

    Introduction:
    At least 23 different variants of IFN-alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.

    Description:
    Interferon-alpha 1a Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19.4 kDa.
    The Interferon-alpha 1a contains Valine residue at position 114.
    The IFN-a 1a is purified by proprietary chromatographic techniques.

    Source:
    Escherichia Coli.

    Physical Appearance:
    Sterile Filtered White lyophilized (freeze-dried) powder.

    Formulation:
    Lyophilized from a (1 mg/ml) solution in containing 1X PBS pH-7.4.

    Solubility:
    It is recommended to reconstitute the lyophilized IFN alpha 1a in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

    Stability:
    Lyophilized Interferon alpha 1a although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-alpha 1a should be stored at 4°C between 2-7 days and for future use below -18°C.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Please prevent freeze-thaw cycles.

    Purity:
    Greater than 95.0% as determined by:
    (a) Analysis by RP-HPLC.
    (b) Analysis by SDS-PAGE.

    Biological Activity:
    The specific activity as determined in a viral resistance assay viral ressistance assay was found to be 1 x 108 IU/ mg.

    Amino Acid Sequence:
    CDLPETHSLD NRRTLMLLAQ MSRISPSSCL MDRHDFGFPQ EEFDGNQFQK APAISVLHEL IQQIFNLFTT KDSSAAWDED LLDKFCTELY QQLNDLEACA MQEERVGETP LMNVDSILAV KKYFRRITLY LTEKKYSPCA WEVVRAEIMR SLSLSTNLQE RLRRKEUsage:
    ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.