上海佰世凯化学科技有限公司

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现货 Ascomycin(FK 520)/子囊霉素

现货 Ascomycin(FK 520)/子囊霉素

参考价格:索要报价
品  牌:chembest
产品型号:C13319 (98%)
所在地区:华东 上海
上架时间:2017-04-26
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详细说明

Ascomycin(FK 520)/子囊霉素
Molecula Formula:C43H69NO12
Molecular Weight: 792.01    
Appearance: White lyophilised solid
Purity:98%
CAS[104987-12-4]

Biological Activity:
Analog of FK 506;binds to FK 506-binding protein 12 (FKBP12) in order to inhibit calcineurin phosphatase activity (IC50 = 49 nM) and activation of nuclear factor of activated T cells (NFAT). Displays antifungal and immunosuppressive activities.

References:
1.Hatanaka et al (1988) FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. II. Fermentation, isolation and physicochemical and biological characteristics. J.Antibiot (Tokyo). 41 1593.

(产品仅适用于科学实验,不得用于其他目的).