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 RN 1 dihydrochloride(RN-1 2HCL) CAS No: 1781835-13-9
  • RN 1 dihydrochloride(RN-1 2HCL) CAS No: 1781835-13-9
  • RN 1 dihydrochloride(RN-1 2HCL) CAS No: 1781835-13-9

    参考价格: ¥0.00
    品  牌:ChemBest
    产品型号:C14114
    适用范围:高教
    所在地区:上海
    上架时间:2017年04月26日
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    Product Name: RN 1 dihydrochloride(RN-1 HCL)

    Synonyms: LSD1 Inhibitor IV, RN-1,HCl;BHC110 Inhibitor IV;KDM1 Inhibitor IV;MOA Inhibitor III

    Chemical Name: 1-(4-methyl-1-piperazinyl)-2-[[(1R*,2S*)-2-[4-phenylmethoxy)phenyl]cyclopropyl]amino]ethanone dihydrochloride

    Molecular Formula:C23H29N3O2.2HCl
    Molecular Weight:452.42
    CAS No.:1781835-13-9
    Storage:Store at -20°C
    Solubility:Soluble to 20 mM in water and to 20 mM in DMSO with gentle warming
    Appearance: Yellow solid
    Purity: >98% by HPLC
    Biological Activity
    Potent lysine specific demethylase 1 (LSD1) inhibitor (IC50 = 70 nM). Exhibits selectivity for LSD1 over MAO-A and MAO-B (IC50 values are 0.51 and 2.79 μM for MAO-A and MAO-B, respectively). Impairs long-term, but not short-term memory in mice. Brain penetrant following systemic administration.