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4008190228-0125
 Cariporide/卡立泊来德 CAS:159138-80-4
  • Cariporide/卡立泊来德 CAS:159138-80-4
  • Cariporide/卡立泊来德 CAS:159138-80-4

    参考价格: ¥0.00
    品  牌:ChemBest
    产品型号:C16477
    适用范围:高教
    所在地区:上海
    上架时间:2018年07月30日
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    Product Name:Cariporide/卡立泊来德

    CAS:159138-80-4

    Synonym: N-(Diaminomethylene)-4-isopropyl-3-(methylsulfonyl)benzamide
    Molecular Formula:C12H17N3O3S

    Molecular Weight:283.35

    Appearance: Powder

    Purity: ≥98%

    Application: An NHE-1 inhibitor that blocks apoptosis in cardiac muscle cells

    Biologicalactivity:

    Cariporide is a NHE-1 (sodium-hydrogen exchanger isoform-1) inhibitor. Rat studies indicate that cariporide blocks apoptosis of cardiac muscle cells. Additional studies show that the compound interacts with and weakens mitochondrial Ca2+ overload and the permeability transition pore (PTP).