Catalog Number : Rs-0657R
Quantity size : 0.2ml (dilute with pH 7.4 0.01 M PBS or antibody diluent )
Background: Multidrug resistance-associated protein 1 (MRP1) is an ATP binding cassette (ABC) transporter, that confers resistance to many natural product chemotherapeutic agents and can transport structurally diverse conjugated organic anions. May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Confers resistance to anticancer drugs. Transports LTC4. May protect milk against xenobiotics (By similarity). Subcellular location at Membrane; multi-pass membrane protein. Tissue specificity: Lung, testis and peripheral blood mononuclear cells. Belongs to the ABC transporter family. Conjugate transporter (TC 3.A.1.208) subfamily. multidrug resistance protein 1 (MRP1)
Specificity : · anti- MRP1 is a rabbit polyclonal antibody unconjugated
· specific for MRP1 of human, rat and mouse
· epitope mapping near the amino terminus of MRP1 of human, rat and mouse origin
· use for western blotting, elisa, immunoprecipitation
· Protein G affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt:170kDa
Application: · Western blotting 1:100-500
· Immunohistochemistry 1:100-500
· ELISA 1:500-1000
· Optimal working dilutions must be determined by the end user.
Storage: Store at -20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.
Important Note: This product as supplied is intended for research use only, not for use in
human, therapeutic or diagnostic applications.