上海叶舟生物科技有限公司

 Fludarabine 原装
  • Fludarabine 原装
  • Fludarabine 原装

    参考价格: ¥2160.0000
    品  牌:Affix
    产品型号:AF3036 (25 MG)
    所在地区:上海
    上架时间:2012/8/29 14:19:46
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    Fludarabine 原装
    产品名称:Fludarabine
    产品货号:Affix  AF3036
    产品规格:25 MG     
    Technical Data
    Chemical Name 9-β-D-Arabinofuranosyl-2-fluoro-9H-p urin-6-amine
    Biological Description Fludarabine is a organic compound (purine analog) that inhibits DNA synthesis.Exhibits antiproliferative activity (IC50 < 3 μM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Displays anticancer activity against hematological malignancies in vivo. Fludarabine (Fludara) can also induce pro-inflammatory stimulation of monocytic cells, as evaluated by increased expression of ICAM-1 and IL-8 release.
    Molecular Weight 285.2 daltons
    Molecular Formula C10H12FN5O4
    Solubility Soluble in DMSO
    Purity >99 %
    Storage instructions Up to one week at 4°C or six months at -20°C.
    CAS No. 21679-14-1 
    References Torella et al (2007) Fludarabine prevents smooth muscle proliferation in vitro and neointimal hyperplasia in vivo through specific inhibition of STAT-1 activation. Am.J.Physiol.Heart Circ.Physiol. 292 H2935.