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VPS9-derived CUE Domain (Agarose Immobilized)
  • VPS9-derived CUE Domain (Agarose Immobilized)
  • VPS9-derived CUE Domain (Agarose Immobilized)

    产品报价: 4263
    品  牌:Biomol
    产品型号:BML-UW9450-0500 (0.5 mL)
    所在地区:上海
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    详细说明

    VPS9-derived CUE Domain (Agarose Immobilized)
    产品名称:VPS9-derived CUE Domain (Agarose Immobilized)
    规格:0.5 mL
    货号:BML-UW9450-0500
    厂商:Biomol
    产品介绍:
    Product Specification
    Source: Synthetic peptide corresponding to residues 394-451 of yeast Vps9 coupled to activated agarose at a concentration of 2mg/ml of settled resin.
    Long Term Storage: +4°C
    Miscellaneous/General: Vps9p is a Saccharomyces cerevisiae exchange factor for the yeast Rab5 GTPase homolog Vps21p, and is known to promote mono-ubiquitylation. Vps9p contains a CUE domain, which shares structural similarity to ubiquitin-associated (UBA) domains. The CUE domain of the yeast Cue2 protein binds a region of ubiquitin that includes the hydrophobic patch , Leu8-Ile44-Val70, and encompasses Lys48, a site of polyubiquitin chain formation. Studies have demonstrated that, in addition to binding mono-ubiquitin, an isolated CUE domain can bind multi-ubiquitin chains and ubiquitylated substrates.
     

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