Selective inhibitor of Brutons tyrosine kinase (BTK). Inhibits the catalytic activity of BTK as well as the interaction between BTK and PKCßII, in intact cells and in cell-free systems, without affecting the activity of PKC. Terreic acid has little or no effect on the activities of Lyn, Syk, PKA, casein kinase I, ERK1, ERK2 and p38 kinase. A useful tool in studying the role of BTK in cellular signaling.
Purity: 99% (TLC)
Long Term Storage: -20°C
Appearance: Pale yellow solid.
Solubility: Soluble in water (3mg/ml with warming and stirring).
Alternative Name: (1R,6S)-3-Hydroxy-4-methyl-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione
Biomol Terreic acid BML-EI328-0001 1 mg -20°C 819
Biomol Terreic acid BML-EI328-0005 5 mg -20°C 3339