产品名称：ERK1/ERK2 (phosphorylated), mAb (AMK1)
The extracellular signal-regulated kinases (ERKs), previously known as MAP (mitogen-activated protein) kinases, are members of a family of proline-directed serine/threonine kinases that are activated by dual phosphorylation of conserved threonine and tyrosine residues within a characteristic Thr-X-Tyr peptide motif. ERK1 (p44) and ERK2 (p42) acquire full enzymatic activity upon phosphorylation of both threonine and tyrosine residues with the motif Thr-Glu-Tyr.
Long Term Storage: -20°C
Application: Western Blot
Alternative Name: MAP kinases
Immunogen: Synthetic peptide containing the motif pThr-Glu-pTyr.
Specificity: Recognizes the pThr-Glu-pTyr motif of activated mammalian ERK1/2. Does not cross-react with non-activated MAP kinases or with the phosphorylated motifs of SAPK/JNK (Thr-Pro-Tyr) or p38 kinases (Thr-Gly-Tyr).