SEW-2871 is a novel, potent EDG receptor agonist structurally unrelated to sphingosine-1-phosphate and is highly selective for the human S1P1 receptor. It inhibits lymphocyte recirculation in vivo and produces immunosuppression without associated bradycardia which is induced by other less selective S1P agonists. In mice SEW-2871 blocked TNFα induced monocyte adhesion to endothelium.
Long Term Storage: Ambient
Biomol SEW-2871 BML-LP106-0010 10 mg Ambient 735
Biomol SEW-2871 BML-LP106-0050 50 mg Ambient 2919