规格: 1 mg
名称: BETA Amyloid 1-40 aβ D23N TFA recombinant human;BETA AMYLOID 1-40 D23N TFA 原装正品
Product Overview: Beta Amyloid (1-40), mutant, D23N, TFA
MOL. WT.: 4330.79 Da by Mass Spec Analysis (theoretical 4328.88)
PEPTIDE CONTENT: 1 mg per vial; salt content is <10%
COUNTER ION: TFA
Application Notes: Different researchers claim enhanced activity due to different salts.
The TFA salt is what has been the industry standard.
The HFIP makes the beta-amyloid homogenously monomeric.
The NaOH apparently make it monomeric too and is also water soluble, which the TFA salt and HFIP are not.
The HCl salt is supposed to be more biological, as TFA is not found in the body.
By offering the different salts, it lets the researchers duplicate the different assays that have been developed by other researchers (see below).
TFA: Shu-chuan Jao, S-C, et. al. 1997, Amyloid; Int J Exp. Clinical Invest. 4, 231
HFIP: Stine, W.B. et. al. 2003, J. Biol. Chem, 278, 11612
NaOH: Fezoui, Y., et. al. 2000, Amyloid, 7, 166
HCL: Kanek, I and Tutumi, S., 1997, J. Neurochem, 68, 438