Background Information: A cell-permeable pyridyl methylsulfinyl benzimidazole compound that acts as selective proton pump inhibitor. Behaves as a prodrug by undergoing an acid-catalyzed rearrangement to a thiol-reactive cationic sulfenamide that inhibits (H+, K+)-ATPase in the gastric milieu. An aryl hydrocarbon-like inducer of cytochrome P450 secretion in human liver.
Presentation: Tan to off-white solid. Packaged under inert gas.
Contaminants: Heavy metals: ≤20 ppm
Properties: Solubility: DMSO (25 mg/ml)
Molecular Weight: 345.4
Gene Symbol: ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B1, ATP1B2, ATP1B3, ATP1B4
Empirical Formula: C17H19N3O3S
Purity: >94% by HPLC
Storage Conditions: Shipped at Ambient Temperature. Store at +2 - 8°C.