Background Information: A cell-permeable, non-peptidic, and highly selective calpain inhibitor directed towards the calcium binding sites of calpain. Displays over 20-fold greater selectivity for calpain-1 (Cat. Nos. 208712 and 208713) over calpain-2 (Cat. Nos. 208715 and 208718) (Ki values: 260 nM and 5.33 µM, respectively). Has been shown to prevent cycloheximide-induced apoptosis.
Molecular Weight: 237.3
Presentation: Orange solid. Packaged under inert gas.
Storage Conditions: Shipped at Ambient Temperature. Store at -20°C.
Properties: Solubility: DMSO (200 mg/ml) or Methanol (5 mg/ml).
Gene Symbol: CAPN1, CAPN2
Empirical Formula: C11H8FNO2