产品名称：anti-mouse/human ZAP-70 Biotin 1E7.2
Also known as: ZAP70
Isotype IgG1, kappa
Description: The 1E7.2 antibody reacts with human and mouse ZAP-70, the TCRζ-associated protein-70. ZAP-70 is a cytosolic protein tyrosine kinase (PTK) and a member of the Syk family of proteins. It is expressed in T and NK cells and is required for TCR signaling and development. ZAP-70 interacts with the TCR complex by binding to tyrosine-phosphorylated immunoreceptor tyrosine-based activation motifs (ITAMs) present in the invariant subunits of the TCR complex. Following activation, ZAP-70 is phosphorylated on several tyrosine residues by two mechanisms; an autophosphorylation and a transphosphorylation by the Src family tyrosine kinase Lck1-3.
eBioscience 13-6695-82 anti-mouse/human ZAP-70 Biotin 1E7.2 100 ug 2268
eBioscience 13-6695-80 anti-mouse/human ZAP-70 Biotin 1E7.2 25 ug 1068