Alternative Name: HBGR, glutamate receptor, AMPA
Long Term Storage: +4°C
Immunogen: Synthetic peptide corresponding to the sequence near the C-terminus of human GluR1.
Application: Immunohistochemistry (1:50)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human, mouse and rat GluR1.
Purity Detail: Affinity purified.
Formulation: Liquid. In 10mM PBS, pH 7.4, containing BSA and sodium azide.
Miscellaneous/General: Glutamate receptors constitute the principal excitatory neurotransmitter receptors in the brain. Two classes of Glutamate receptors exist: inotropic receptors and Metabotropic receptors. Inotropic glutamate receptors are oligomeric complexes which are ligandgated calcium channels. Metabotropic glutamate receptors, on the otherhand, are G-protein coupled receptors (GPCRs), which when activated can activate phospholipases or adenylylcyclase, depending on the neuron.