Alternative Name: signal transducer and activator of transcription
Long Term Storage: -20°C
Immunogen: Synthetic peptide corresponding to a portion of human Stat1 phosphorylated at Ser727.
Application: Western Blot (1µg/ml, ECL)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human, mouse (weak), pig (weak), hamster (weak) and monkey (weak) Stat1. Detects a band of ~91kDa by Western blot.
Purity Detail: Peptide affinity purified.
Formulation: Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Miscellaneous/General: Stats (Signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, Stats enter the nucleus to regulate transcription of many different genes.