上海浩洋生物科技有限公司

 15-deoxy-Δ12,14-PGJ2, pAb
  • 15-deoxy-Δ12,14-PGJ2, pAb
  • 15-deoxy-Δ12,14-PGJ2, pAb

    参考价格: ¥4500.00
    品  牌:ENZO
    产品型号:ADI-915-044-100 (100 ul)
    所在地区:上海
    上架时间:2013年03月01日
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    15-deoxy-Δ12,14-PGJ2, pAb
    产品名称:15-deoxy-Δ12,14-PGJ2, pAb
    规格:100 ul
    货号:ADI-915-044-100
    厂商:ENZO
    产品介绍:
    Alternative Name: Prostaglandin J2
    Host: Rabbit
    Long Term Storage: -20°C 
    Immunogen: 15-deoxy-D12,14-Prostaglandin J2.
    Application: EIA
    Optimal conditions must be determined individually for each application.
    Specificity: Species independent.
    Purity Detail: Sodium sulfate precipitation purified.
    Formulation: Liquid. In PBS containing 1.0mg/ml Rabbit IgG and 0.1% sodium azide.
    Miscellaneous/General: 15-deoxy-Delta12,14-Prostaglandin J2 (15-d-PGJ2) is one of the ultimate dehydration products of PGD2, formed via the intermediate Delta12-PGJ2. 15-d-PGJ2 is physiologically present in body fluids at concentration of 10-12 to 10-9 M, but increases dramatically under stress such as infection and inflammation. 15-d-PGJ2 exerts both pro- and anti-inflammatory effects in a cell-type and concentration-dependent manner, with many of these effects mediated via binding to the gamma isoform of the peroxisome proliferators-activated receptor (PPAR-gamma). 15-d-PGJ2 appears to induce HO-1 expression by a PPAR-gamma-independent mechanism mediated by the generation of reactive oxygen species (ROS).