产品名称：MKK7, mAb (10F7)
Alternative Name: MAP2K7, Map kinase kinase 7
Long Term Storage: -20°C
Immunogen: Synthetic peptide corresponding to the sequence near the amino terminus of MKK7 (MAP2K7) conjugated to hemocyanin.
Application: ELISA (0.1µg/ml)
Western Blot (0.5µg/ml, ECL)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human, mouse, rat and dog MKK7. Detects a band of ~45kDa by Western blot.
Purity Detail: Thiophilic adsorption and size exclusion chromatography purified.
Formulation: Lyophilized from 1ml of 2x PBS containing 0.09% sodium azide, PEG, and sucrose.
Reconstitution: Reconstitute with 1ml water (15 minutes at room temperature).
Use/Stability: Stable at -80°C up to 1 year, at 4°C up to 3 months.
Miscellaneous/General: Members of the MAP kinase family of protein kinases (e.g. p38 and Jnk) are subject to dual phosphorylation of a conserved T-X-Y motif in their activation domain by upstream members of the MAP/ERK kinase (MEK/MKK) family. MKK3 and MKK6 phosphorylate p38 in response to cytokine stimulation and cellular stress, while MKK7 and MKK4 activate the Jnk kinases by phosphorylation of the threonine and tyrosine residues, respectively.