Long Term Storage: +4°C
Immunogen: Synthetic peptide corresponding to the sequence near the middle of human TSC1.
Application: Immunocytochemistry (2µg/ml)
Western Blot (1µg/ml)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human, mouse and rat TSC1.
Purity Detail: Peptide affinity purified.
Formulation: Liquid. In PBS containing 0.02% sodium azide.
Miscellaneous/General: Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 (Hamartin) or TSC2 (Tuberin) tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases mTOR signaling via stimulation of Rheb GTPase activity