Alternative Name: toll-like receptor
Long Term Storage: +4°C
Immunogen: Synthetic peptide corresponding to the sequence near the N-terminus of human TLR1.
Application: Immunohistochemistry (10µg/ml)
Western Blot (1-2µg/ml)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human and mouse TLR1.
Purity Detail: Ion exchange purified.
Formulation: Liquid. In PBS containing 0.02% sodium azide.
Miscellaneous/General: The TLRs (Toll-like receptors) are a group of evolutionarily conserved pattern recognition molecules that play a key role in host defense during microbial infection by regulating both innate and adaptive immune responses. TLRs are type I transmembrane proteins with ectodomains containing interspersed leucine-rich repeat (LRR) motifs that are involved in the recognition of various microbial ligands.