产品名称：TNF receptor 1, pAb
Alternative Name: tumor necrosis factor receptor, TNF-R1
Long Term Storage: -20°C
Immunogen: Synthetic peptide corresponding to a portion of mouse TNF-R1. The sequence is completely conserved in rat and human.
Application: Immunohistochemistry (paraffin sections)
Western Blot (1:1000, ECL)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human, mouse, rat, bovine, dog, Drosophila, hamster, monkey, pig, rabbit, sheep, Xenopus and yeast TNF-R1. Detects a band of 55kDa by Western blot.
Purity Detail: Peptide affinity purified.
Formulation: Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Miscellaneous/General: Tumor necrosis factor alpha (TNF-α), also known as cachectin, is a 17.5 kDa 157 amino acid member of the TNF superfamily of cytokines that is a potent lymphoid factor with effects on a wide range of target cells. Active TNFalpha is produced in both soluble and membrane-anchored trimers by macrophages, NK cells, and T- and B-lymphocytes. TNF exerts proinflammatory signals via binding and inducing trimerization of TNF-receptor1 (TNF-R1) expressed on most normal and transformed cells, or to TNF-receptor 2 (TNF-R2), expressed on endothelial and most immune cells. TNF signaling regulates hematopeiesis, differentation, endothelial cell activation, apoptosis, lipid metabolism, tumor progression, and immune suveillance, and dysregulation of TNF or its receptors is implicated in numerous disease states including cancer, osteoporosis, autoimmune disease, diabetes, and atherosclerosis.
ENZO ADI-CSA-815-D TNF receptor 1, pAb 50 ug 2850
ENZO ADI-CSA-815-F TNF receptor 1, pAb 200 ug 5550