上海浩洋生物科技有限公司

 BX795
  • BX795
  • BX795

    参考价格: ¥2086.00
    品  牌:invivogen
    产品型号:tlrl-bx7 (5 mg)
    所在地区:上海
    上架时间:2013年03月14日
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    BX795
    产品名称:BX795
    规格:5 mg
    货号:tlrl-bx7
    厂商:invivogen
    产品介绍:
    Working concentration: 10 nM -1 μM
    Endotoxin level: <0.125 EU/mg
    Solubility: DMSO (10 mg/ml)
    Formula: C23H26IN7O2S
    Molecular weight: 591.5
    TBK1/IKKε inhibitor
    BX795 inhibits the catalytic activity of TBK1/IKKε by blocking their phosphorylation. BX795, an aminopyrimidine compound, was developed as an inhibitor of 3-phosphoinositide-dependent kinase 1 (PDK1) [1]. It was recently shown to be a potent inhibitor of the IKK-related kinases, TANK-binding kinase 1 (TBK1) and IKKε, and hence of IRF3 activation and IFN-β production [2, 3].