上海浩洋生物科技有限公司

 CL264 Rhodamine
  • CL264 Rhodamine
  • CL264 Rhodamine

    参考价格: ¥1652.00
    品  牌:invivogen
    产品型号:tlrl-rc264 (100 μg)
    所在地区:上海
    上架时间:2013年03月15日
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    CL264 Rhodamine
    产品名称:CL264 Rhodamine
    规格:100 µg
    货号:tlrl-rc264
    厂商:invivogen
    产品介绍:
    Specificity: human/mouse TLR7 agonist
    Working concentration: 1 -10 μg/ml
    Endotoxin level: EndoFit™ (<0.001 EU/μg)
    Solubility: 10 mg/ml in DMSO
    CL264 Rhodamine is provided as a pink lyophilized and shipped at room temperature. Store at -20°C. Upon resuspension, CL264 Rhodamine should be aliquoted and stored at -20°C. Lyophilized product is stable 1 year at -20°C when properly stored. Resuspended product is stable 6 months at -20°C. Avoid repeated freeze-thaw cycles.
    CL264 is a novel 9-benzyl-8 hydroxyadenine derivative containing a glycine on the benzyl group (in para). Similarly to SM360320, CL264 induces the activation of NF-κB and the secretion of IFN-α in TLR7-expressing cells [1]. CL264 is a TLR7-specific ligand, it does not stimulate TLR8 even at high concentrations (> 10 µg/ml). In TLR7-transfected HEK293 cells, CL264 triggers NF-κB activation at a concentration of 0.1 µM which is 5-10 times less than imiquimod. CL264 is labeled with Rhodamine on the acid group of the glycine via a HEX spacer. CL264 Rhodamine can be used confocal laser-scanning microscopy or flow cytometry.