Specificity: human / murine TLR9 agonist
Working concentration: 5 µM (10 μg/ml)
Endotoxin level: EndoFit™ (<0.001 EU/μg)
Solubility: 5 mg/ml in water
ODN M362 sequence
5’-tcgtcgtcgttc:gaacgacgttgat-3’ (25 mer)
Note: Bases are phosphorothioate (nuclease resistant), palindrome is underlined.
ODN M362 is shipped at room temperature and should be stored at -20 °C for up to 1 year. Upon resuspension, prepare aliquots of ODN M362 and store at -20°C. Resuspended product is stable 6 months at -20°C when properly stored. Avoid repeated freeze-thaw cycles.
CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs). These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA. CpG ODNs are recognized by Toll-like receptor 9 (TLR9) leading to strong immunostimulatory effects.
invivogen tlrl-m362 ODN M362 200 µg 2310
invivogen tlrl-m362-1 ODN M362 1 mg 9280
invivogen tlrl-m362-5 ODN M362 5 mg 29920