产品名称：Poly(dG:dC) / LyoVec
Activity: RIG-I & CDS agonist
Formulation: naked or complexed with the transfection reagent LyoVec™
CAS number: 90385-88-9
Solubility: 2 mg/ml in physiological water
Endotoxin level: EndoFit™ (<0.001 EU/µg)
Poly(dG:dC) is a poly(deoxyguanylic-deoxycytidylic) acid sodium salt. It is a repetitive synthetic double-stranded DNA sequence of poly(dG-dC)•poly(dC-dG). Poly(dG:dC) is a synthetic analog of the Z-DNA form. It has been reported to be recognized by LRRFIP1.
It activity has been tested using the reporter cell line B16-Blue™ IFNα/β.
Poly(dG:dC) is also available complexed with the cationic lipid transfection reagent LyoVec™ to facilitate its uptake.