3D单分子荧光成像系统-SAFe 360

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品　　牌：abbelight

产品型号：SAFe 360

制造厂商：abbelight

适用范围：高教

所在地区：法国

　　SAFe 360是法国abbelight公司推出的一款基于单分子定位的显微成像（SMLM）的新型3D单分子成像系统，它的DAISY技术整合了散光技术和超临界角光技术，能够大的提高定位精度，xyz三轴定位精度高达15nm，可以提供高清晰三维亚细胞结构图像，支持同时多四色成像，可以用于细胞纳米三维成像，观测高清晰亚细胞器结构，实时研究不同的结构功能蛋白的共定位信息，在单分子水平研究分子动力学反应以及细胞间的相互作用等。

3D单分子荧光成像系统-SAFe 360

设备参数

　　+  成像模式：PALM、STORM、PAINT、smFRET 、SPT

　　+  光源模式：Epi、TIRF、HILO

　　+  超高分辨率：15 nm的XYZ轴分辨率

　　+  超大视野：200 × 200 μm2的视野

　　+  一次可同时采集1.2 μm深度图像信息

　　+  大图像深度：10 μm

　　+  实时漂移矫正

　　+  多四色同时成像

　　+  活细胞成像模式

Now We See......

配套试剂

发表文献列表

　　[1] Radhakrishnan, A. V., et al. "Single-Protein Tracking to Study Protein Interactions During Integrin-Based Migration." The Integrin Interactome. Humana, New York, NY, (2021). 85-113.

　　[2] Jouchet, Pierre, et al. "Nanometric axial localization of single fluorescent molecules with modulated excitation." Nature Photonics(2021): 1-8.

　　[3] Pernier, Julien, et al. "Myosin 1b flattens and prunes branched actin filaments." Journal of cell science133.18 (2020).

　　[4] Jimenez, Angélique, Karoline Friedl, and Christophe Leterrier. "About samples, giving examples: optimized single molecule localization microscopy." Methods 174 (2020): 100-114.

　　[5] Mau, Adrien, et al. "Fast scanned widefield scheme provides tunable and uniform illumination for optimized SMLM on large fields of view." bioRxiv(2020).

　　[6] Orre, Thomas, et al. "Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions." bioRxiv(2020).

　　[7] Cabriel, Clément, et al. "Combining 3D single molecule localization strategies for reproducible bioimaging." Nature communications10.1 (2019): 1980.

　　[8] Woodhams, Stephen G., et al. "Cell type–specific super-resolution imaging reveals an increase in calcium-permeable AMPA receptors at spinal peptidergic terminals as an anatomical correlate of inflammatory pain." Pain160.11 (2019): 2641-2650.

　　[9] Belkahla, Hanen, et al. "Carbon dots, a powerful non-toxic support for bioimaging by fluorescence nanoscopy and eradication of bacteria by photothermia." Nanoscale Advances(2019).

　　[10] Denis, Kevin, et al. "Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease." Nature microbiology4.6 (2019): 972.

　　[11] Szabo, Quentin, et al. "TADs are 3D structural units of higher-order chromosome organization in Drosophila." Science advances4.2 (2018): eaar8082. 

　　[12] Boudjemaa, Rym, et al. "Impact of bacterial membrane fatty acid composition on the failure of daptomycin to kill Staphylococcus aureus." Antimicrobial agents and chemotherapy62.7 (2018): e00023-18.

　　[13] Culley, Sian, et al. "Quantitative mapping and minimization of super-resolution optical imaging artifacts." Nature methods15.4 (2018): 263.

　　[14] Berger, Stephen L., et al. "Localized myosin II activity regulates assembly and plasticity of the axon initial segment." Neuron97.3 (2018): 555-570.

　　[15] Cabriel, Clément, et al. "Aberration-accounting calibration for 3D single-molecule localization microscopy." Optics letters43.2 (2018): 174-177. 

　　[16] Bouissou, Ana?s, et al. "Podosome force generation machinery: a local balance between protrusion at the core and traction at the ring." ACS nano11.4 (2017): 4028-4040. 

　　[17] Sellés, Julien, et al. "Nuclear pore complex plasticity during developmental process as revealed by super-resolution microscopy." Scientific reports7.1 (2017): 14732.

　　[18] Bourg, Nicolas, et al. "Direct optical nanoscopy with axially localized detection." Nature Photonics9.9 (2015): 587. 

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